New: View a video of Dr. Temenoff explaining current research in the lab.

Our current areas of research are:

  • Use combination of well-defined biomaterial environment and tensile culture bioreactor to:
    1. Understand effects of mechanical forces on differentiation of mesenchymal stem cells toward the tendon/ligament lineage
    2. Elucidate effects of local environment on mechanotransduction by mesenchymal stem cells
  • Tensile culture system for applying cyclic mechanical strain
  • Characterize localized extracellular matrix production at interfaces in orthopaedic tissues
  • Patellar tendon, collagen type I (Jeremy Lim) Cartilage, collagen type I
    (Jeremy Lim)
  • Develop cell carrier materials that work in concert with local mechanical forces to promote regeneration of orthopaedic interfaces, such as tendon/ligament - bone.
  • A laminated OPF hydrogel.

Diagram of the ligament-bone interface


Information for undergraduate students

If you are interested in conducting research as an undergraduate student in the Temenoff lab, please click here for more information.