New: View a video of Dr. Temenoff explaining current research in the lab.
Our current areas of research are:
- Use combination of well-defined biomaterial environment and tensile culture bioreactor to:
- Understand effects of mechanical forces on differentiation of mesenchymal stem cells toward the tendon/ligament lineage
- Elucidate effects of local environment on mechanotransduction by mesenchymal stem cells
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Tensile culture system for applying cyclic mechanical strain - Characterize localized extracellular matrix production at interfaces in orthopaedic tissues
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Patellar tendon, collagen type I (Jeremy Lim) Cartilage, collagen type I
(Jeremy Lim) - Develop cell carrier materials that work in concert with local mechanical forces to promote regeneration of orthopaedic interfaces, such as tendon/ligament - bone.
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A laminated OPF hydrogel.
Diagram of the ligament-bone interface
Information for undergraduate students
If you are interested in conducting research as an undergraduate student in the Temenoff lab, please click here for more information.

